The theory is that cycling prevents receptor desensitization and reduces cumulative side effect burden
This is why proper sterile technique and minimizing the time the vial is open are so important
Since thats not practical (except in cases of Xylitol poisoning when dogs are often hospitalized see sidebar), I typically use a topical gel preparation placed on a hairless area to be absorbed through the skin
Enrichr: a comprehensive gene set enrichment analysis web server 2016 update
The mouse was placed on a balance beam (length 100 cm, width 12 mm) located at a height of 50 cm, and the time to reach the end of the balance beam along with the number of foot slips during the movement were measured
Mangum KD, Li Q, Hartmann K, Bauer TM, Wolf SJ, Shadiow J, Moon JY, Barrett E, Joshi A, de Saldana G et al