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Dose-related side effects appear more pronounced with oral formulations due to higher required doses

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They are not approved for human or animal use of any kind

ii) Utilizing the steric hindrance conferred by dimerization reduces protease access to the active site and significantly improving stability against proteases 49,50

Implications for the treatment of Parkinsons disease

If the Meibomian gland obstructions are not mechanically cleared the condition will progress