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Journal of Toxicology and Environmental Health

In a notable study published in The Lancet , participants taking tesofensine over six months achieved an average weight loss of 10-12% of their initial body weight, with higher doses showing more pronounced effects

But recovery doesnt come as easily

Recently, neural activity mediated by NMDA-receptors (NMDAR) has been coupled with transcriptional activation of glutamate-cysteine ligase, a key enzyme in GSH production, leading to a sustained GSH-based protection against an oxidative insult 26

The biggest challenge with this specific nutrient is bioavailability

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