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This review is based on studies that are either small or non-randomized, and have involved multiple different GLP-1RAs

These insights may help contextualize supplementation decisions but should always be discussed with your qualified healthcare provider

Moreover, while GLP-1 analogs were originally designed for glycemic control in diabetic patients and subsequently applied to obesity, their utility has expanded into other metabolic conditions like NASH (fatty liver), and even cardiovascular disease prevention

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Conditions such as Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), Fibromyalgia (FM), and Gulf War Syndrome (GWS) are examples of these chronic illnesses that are triggered by different factors but share overlapping clinical symptoms, in particular profound fatigue (see Figure 1)