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Bee venom phospholipase A2 alleviates collagen-induced polyarthritis by inducing Foxp3+ regulatory T cell polarization in mice

You will receive the first two 4-week dosing cycles in the office (8 injections) and will be taught how to perform your own injections to continue at home after the initial eight injections

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Primary endpoint: Mean change in A1C from baseline at Week 40

Elevated levels of insulin-like growth factor (IGF)-I in serum rescue the severe growth retardation of IGF-I null mice