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TDP-43 is usually found in the nucleus, but in many cases of ALS it accumulates in the cytoplasm (TDP-43 proteopathy) (Thakur et al

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These compounds are of concern due to their environmental impact, role in global chemical cycles, and effects on taste, odor, and pollution in various applications

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Phosphatidylethanolamine-binding protein 1 (PEBP1) and arachidonate 15-lipoxygenase (ALOX15) can interfere with phospholipid alcohol synthesis and induce ferroptosis [5, 52]