A 2025 University of Virginia study concluded that while GLP-1 drugs significantly reduce body weight and adiposity, they do so "with no clear evidence of cardiorespiratory fitness enhancement"a critical finding given that cardiorespiratory fitness is among the most potent predictors of all-cause and cardiovascular mortality [48]
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doi: 10.1210/en.2018-00004 33 SelvarajahVRobertsonDHansenLJermutusLSmithKCoggiAet al
Bullous pemphigoid induced by dipeptidyl peptidase-4 inhibitors
Comparative effects of proximal and distal small intestinal administration of metformin on plasma glucose and glucagon-like peptide-1, and gastric emptying after oral glucose, in type 2 diabetes
Helps maintain healthy blood sugar