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Furthermore, the physicochemical properties of LLPS enable MLOs to exhibit liquid-like properties, such as fluidity, dynamics of formation and dissolution, partitioning ability, and diffusional properties

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Increased glucose uptake promotes oxidative stress and PKC-delta activation in adipocytes of obese, insulin-resistant mice

Small animal rat model Six-week-old male Sprague-Dawley rats were obtained from Shanghai Lab, Animal Research Center Co

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5.3 Tryptophan metabolites Tryptophan metabolites are generated either through direct decomposition of tryptophan by gut microbiota (e.g., Clostridium, Escherichia coli ) into indole derivatives (such as IPA and indole-3-acetic acid (IAA)) or via host-cell-mediated processes (e.g., indoleamine 2,3-dioxygenase 1(IDO1)-catalyzed kynurenine production, 5-hydroxytryptamine (5-HT) synthesis by enterochromaffin cells) in coordination with microbial metabolism