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Blockade of the chemokine receptor CXCR2 inhibits pancreatic cancer cell-induced angiogenesis
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Future research should focus on developing strategies for selective targeting to minimize effects on normal tissues, understanding mechanisms of resistance and ways to overcome them, and optimizing combination therapies with chemotherapy, radiotherapy, or immunotherapy to enhance efficacy
Whether or not that framing fully resolves the regulatory picture, it is the lens he uses for everything that follows
Discussion In this study, we employed an integrative multi-omics approach to delineate the molecular and metabolic landscape of advanced-stage lipedema, a disabling adipose tissue disorder characterized by chronic pain, inflammation, and progressive fat deposition