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Immediate and long-lasting results Efficacy confirmed by those who try it Self-assessment of 30 women aged 4060, in perimenopause or menopause, who applied the serum twice daily for 28 days and agreed with the following statements

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In other embodiments, a therapeutically effective amount of at least one therapeutic agent, or otic agent, is released from the formulation or composition immediately, or within 1 minute, or within 5 minutes, or within 10 minutes, or within 15 minutes, or within 30 minutes, or within 60 minutes, or within 90 minutes

In some embodiments, a pharmaceutical composition of the present disclosure may be a buffered aqueous formulation