Most patients can continue semaglutide before elective surgery with appropriate risk assessment
These results are directional, not directly translatable
Eliaschewitz, F
As dozens of novel agents currently under study seek new indications, the question arises of whether the traditional practice of two confirmatory trials for every indication expansion remains justified, especially when database study emulations that benchmark against previously conducted, closely related reference trials have yielded aligned results 33,34
The weight loss difference between liraglutide and phentermine is smaller than with semaglutide or tirzepatide, which means the other factors, cost, side effects, duration of treatment, and long-term outcomes, carry more relative weight in the decision
These conditions include type 2 diabetes, high blood pressure, or high cholesterol