They both work to intercept the hunger signals from the brain that tell a patient they are hungry, leading to healthy and regulated weight loss without the need for surgery or invasive treatments
Many of the newer agents in T2D, particularly SGLT2 inhibitors and GLP-1 receptor agonists, are being highlighted for their cardiovascular benefits, which is an important consideration given the risk of heart disease associated with T2D
Monitor Your Energy: If you feel "bone-tired" even after losing weight, it may be time to check your vitamin levels or ensure your thyroid medication dose is still correct
Decreased insulin sensitivity, causing more calories to be stored as fat Hormonal fluctuations in estrogen, progesterone, and cortisol Increased hunger signaling due to changes in ghrelin and leptin A slower resting metabolic rate that resists standard calorie deficits These changes explain why so many women feel trapped in familiar cycles: Losing a few pounds, then regaining them within weeks Experiencing constant cravings despite eating clean Struggling with the fatigue that makes any consistency difficult Weight loss becomes far more achievable when you address the underlying physiology, not just calories in and calories out
Once the needles off, the pen itself cant just go in the trash unless your local rules say its OK
Tsai CJ, Nagata T, Liu CY, Suganuma T, Kanda T, Miyazaki T, Liu K, Saitoh T, Nagase H, Lazarus M, Vogt KE, Yanagisawa M, Hayashi Y (2021) Cerebral capillary blood flow upsurge during REM sleep is mediated by A2a receptors
