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The capacity of GPX4 to influence cell viability through several pathways highlights its potential as a promising therapeutic target for malignancies

10.1016/j.transproceed.2008.10.009 59 HamrounA.LenainR.BignaJ

Abstract Acetaminophen (APAP) is one of the most commonly used analgesics worldwide, and overdoses are associated with lactic acidosis, hepatocyte toxicity, and acute liver failure due to oxidative stress and mitochondrial dysfunction