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5.Detoxification support: Glutathione is involved in the body's natural detoxification processes, helping to eliminate harmful substances and toxins

Lactate dehydrogenase B is required for the growth of KRAS-dependent lung adenocarcinomas

Loss of autophagy in HSCs leads to metabolic stress and altered functionality

These cells recognize antigens presented by MHC II molecules on antigen-presenting cells, such as dendritic cells and macrophages

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In addition to their roles in modulating the immune system, other functions have been attributed to exosomal cargo including enhanced vascular leakiness, fibronectin deposition, and delivery of soluble factors that are involved in ECM remodeling to support formation of a metastatic niche for tumor cells, including melanomas ( Figure 2 ) (104, 109112)