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Some studies indicate that environmental factors, such as nutrition, should additionally be taken into account (Noto et al
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Symptoms of dyspepsia, nausea, vomiting, bloating, diarrhea, and constipation stand out among the gastrointestinal adverse effects described.514 The presence of gastrointestinal adverse effects associated with antidiabetics has an overall impact on the patient with diabetes, given that they can increase the need for medical attention, affect quality of life due to the symptoms they trigger, and modify therapeutic regimens
Weeks 3-8 : Visible reduction in the intensity and size of dark spots and post-inflammatory hyperpigmentation (PIH)
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Additionally, systematic reviews of observational studies have found no evidence of an association between folate exposure during pregnancy and childhood asthma or allergies (80, 81)
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