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The step-wise dose increases exist to manage GI adaptation

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Identification of two missense mutations in the GIP receptor gene: a functional study and association analysis with NIDDM: no evidence of association with Japanese NIDDM subjects

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Fluctuations in blood sugar levels (which happen when someone starts an effective diabetes treatment) can temporarily affect the eyes

Additionally, a secondary analysis revealed a 52% reduction in new-onset type 2 diabetes among participants without baseline diabetes