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Astaxanthin and omega-3 fatty acids individually and in combination protect against oxidative stress via the Nrf2-ARE pathway

doi: 10.1161/JAHA.115.002767 114 ChenMLZhuXHRanLLangHDYiLMiMT

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Oxidative stress increases GSSG concentration and reduces the availability of GSH for coordination of the [FeS] complex, leading to cluster degradation and formation of enzymatically active Grx2 monomers [154]