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Increased ROS levels in human and murine primary RPE [43] and in ARPE-19 cells [44] cultured under HG conditions have been reported

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For acute injuries, the traditional RICE protocol (rest, ice, compression, elevation) emphasizes immediate cold application during the first 48 hours when inflammatory processes are most active

10.1186/1471-2202-11-146 BMC Neurosci

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