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[2] In 2004, Sinclair founded Sirtris Pharmaceuticals along with Andrew Perlman, Christoph Westphal, Richard Aldrich, Richard Pops, and Paul Schimmel

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The enzyme has been identified in a number of higher plants, algae and cyanobacteria (reviewed in Caverzan et al., Arabidopsis thaliana , the reported eight isoenzymes of APX can be categorized into three groups: soluble cytosolic (APX1, APX2, and APX6), (Dbrowska et al., 2002) (Table 2)

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