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Similar content being viewed by others Introduction Several energy-saving adaptations are triggered by the hypothalamus during food deprivation, including increases in skeletal muscle work efficiency, and inhibition of thermogenesis, thyroid and reproductive axes 1,2,3,4,5,6,7

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Research has examined DSIP's interactions with corticotropin-releasing hormone (CRH) and ACTH pathways, with investigators studying how the peptide influences stress hormone cascades in both in vitro and animal model systems

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