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The key milestones are as follows: The FDA granted orforglipron the Commissioner's National Priority Review Voucher, a designation that could compress the standard 10-12 month review period to as little as 1-2 months

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This induction involved four weeks of access to a 20% aqueous fructose solution, followed by daily intraperitoneal injections of freshly prepared streptozotocin (STZ) solution ( at a dosage of 40 mg/kg body weight for five consecutive days

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