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Kidney function decline is a major driver of aging-related morbidity

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Immunologic research , 69 (2), 205-211

then, the speed was increased by increments of 5 m/min, with 2 minutes of rest in between each increment, until the mice reached a speed where they were unable to run for the full 5-minute trial, defined by the mouse taking 25 total foot shocks or remaining on the shock grid for more than 5 consecutive seconds

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