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Berberine also restored protein phosphate 2A (PP2A) activity and glycogen synthase kinase 3 (GSK-3) activity (GSK-3 Tyr216 and Ser9 site phosphorylation increased) (Yu et al., 2011)

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Metformin treatment ameliorates diabetes-associated decline in hippocampal neurogenesis and memory via phosphorylation of insulin receptor substrate 1

[2] [3] Gallstones may be suspected based on symptoms

Such a holistic approach has the potential to not only extend survival but also to improve the quality and resilience of life in gastrointestinal cancer patients