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conducted a randomized, double-blind, placebo-controlled (RDBPC) trial in 146 polysensitized AR pediatric patients randomly stratified into two groups, treated for 4 weeks with compound plus standard treatment or placebo plus standard treatment [63]

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Post-mortem studies of the autistic brain samples showed abnormal changes in the steady-state levels of complexes I-IV in the cingulate gyrus, cerebellum, thalamus, and temporal and frontal cortex [79, 80, 86, 122]

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The intercellular junction serves as the primary channel through which water and other solutes traverse the vascular endothelium

This dual mechanism, akin to the effects of bariatric surgery, aids in weight loss by reducing eating patterns and making it easier for patients to stick to other weight loss strategies like dieting