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Neuropharmacology 170 , 108042 (2020)

As GLP-1 medications like semaglutide and tirzepatide become more widely used for weight management, counterfeit and unsafe products have entered the market

GLP-1 agonists do not directly affect serotonin levels or interfere with Zoloft's mechanism of action, so they should not worsen depression or reduce SSRI effectiveness

INCRETIN HORMONE PHARMACOLOGY AND SIGNALING RESEARCH Understanding how incretin hormones (GIP and GLP-1) coordinate metabolic responses requires investigation of each hormone's specific signaling

The main idea is to create a caloric deficit, usually around 500 calories per day, while incorporating consistent physical activity and addressing the mental and emotional factors that influence eating habits

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