Contrary to RANKL and LIGHT, which appear to promote MASLD, tumor necrosis factor weak inducer of apoptosis (TWEAK) was shown to downregulate TNF--induced inflammatory signals and ameliorate IR and hepatic steatosis [54], thus implying a potentially beneficial effect in MASLD
Author contributions YK: Conceptualization, Data curation, Investigation, Methodology, Project administration, Validation, Writing original draft, Writing review & editing
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Two observational studies have reported that there is an increased urinary excretion of 3-HIA during pregnancy, though other indices of biotin status were not consistently altered (23, 24)