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In addition, body composition changes favor a decline in lean body mass and an increase in fat distribution

Retinopathy is a complication that can occur in people with diabetes, where the blood vessels in the retina become damaged, leading to vision impairment or even blindness

The anorexic action of these hormones is thought at least in part to be mediated through activation of their cognate G-protein coupled receptors (GLP1R and NPY2R, respectively) located on vagal afferent nerve terminals, originating from neurons with somata in the nodose ganglia 2

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