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Intestinal OCT1 transport and metformin pharmacokinetics and efficacy As OCT1 is probably apically expressed it is most likely to influence local concentrations of metformin in the gut (lumen and enterocytes), rather than transfer into the blood

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galloprovincialis (Gonzalez-Rey and Bebianno, 2013), and it did no provoked changes on this activity in the bivalve Perna perna (Cortez et al., 2019)

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