Targeting apoptosis and unfolded protein response: the impact of beta-hydroxybutyrate in clear cell renal cell carcinoma under glucose-deprived conditions
6 Insulin also promotes several other cellular processes, in addition to glucose homeostasis, including regulation of glycogen synthesis, lipid metabolism, DNA synthesis, gene transcription, amino acid transport, protein synthesis and degradation 7
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While these studies provided evidence for a paradigm shift in the role of JNK in APAP hepatotoxicity, there are some reservations that need to be further explored before discarding a role for JNK in APAP-induced liver injury
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