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12 Moreover, lipotoxicity, endotoxin translocation, and chronic low-grade inflammation activate Kupffer cells (KCs) and polarize immune cell populations, 13 contributing to a persistent pro-inflammatory hepatic microenvironment

But it makes me a little sad since I enjoy food. So how exactly are these drugs hijacking the brain space formerly occupied by the siren song of snacks

PLC hydrolyzes phosphatidylinositol 4,5-P(PIP) into 1,2-diacylglycerol (DAG) and inositol 1,4,5-triphosphate (IP)

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Curr Pharmacol Rep 8 , 262280 (2022)