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Guidelines on second- and third-line medicines and type of insulin for the control of blood glucose levels in non-pregnant adults with diabetes mellitus

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Patients with T2DM who received GLP-1RAs for the first time between January 1, 2020, and May 31, 2023, were included

found that IL-33 could activate the NF-kB signaling pathway, which in turn could downregulate caspase-3 expression, while increase the expressions of Bcl-2 and Bax, leading to reduce the sensitivity of acute myeloid leukemia to chemotherapy (127)

Some individuals tolerate one option better than the other