The GLP-1 receptor agonists (e.g., liraglutide, semaglutide, dulaglutide, and the dual GLP-1/GIP agonist tirzepatide) were first developed for T2DM, and they act by mimicking the incretin hormone GLP-1, which increases glucose-dependent insulin secretion, decreases glucagon secretion, and prolongs gastric emptying [5]
In the OASIS 4 clinical trial, the Wegovy pill produced an average weight loss of 16.6% of body weight over 64 weeks
Sequence clinicians used to check their eligibility for using GLP-1 medications such as semaglutide after assessing their body mass index, blood sugar levels, medical history, and comorbid conditions
In addition, there is preliminary evidence that these drugs also have a beneficial effect on psoriasis, especially in individuals who have type 2 diabetes
Adopt a healthy lifestyle, including a balanced diet and regular exercise, to support liver and overall health
The decision to continue, adjust, or discontinue Ozempic should be made collaboratively, weighing the benefits of improved glycaemic control against the impact of gastrointestinal adverse effects on patient wellbeing