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Shooting a stream of water directly onto the lyophilized cake can physically damage the peptide structure

A.Libardi Miranda FurtadoC.Silveira RamosE.et al (2021)

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The frequency can range from weekly to monthly, depending on your lifestyle and how your body responds

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For a more comprehensive review on the various dietary antioxidants that can form a pro-oxidant state, please refer to Yordi et al