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Some studies demonstrate an arrestin-independent but AP2- and clathrin-dependent internalization mechanism, while others suggest that arrestin is required ( Using a BRET-based assay, our data show that GLP-1R undergoes rapid agonist-stimulated endocytosis, whereas a loss of GIPR cell surface expression occurred at a significantly slower rate
PMID: 29181666 Severyanova L, Plotnikov DV
[DOI] [PMC free article] [PubMed] [Google Scholar] 24.Burrus B.M., Moscicki B.M., Matthews T.D., Paolone V.J
Speed up the breakdown of fat using your body's metabolism
Diabetes Care 38(5):752759
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