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In general, the interpretation of the overall evidence is difficult due to discrepancy in the results according to the exposure (i.e., B12 intake versus plasma levels), cancer types, and study designs

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While Lipo-B12 injections are generally well-tolerated, some people might experience mild redness at the injection site, or sometimes a slight increase in energy that can feel a bit much at first

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Studies in rodent systems reported relative oral bioavailability near 30 %, whereas intact TB-500 remained below 1 %