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To view digital features for this article go to Introduction Since the first patients with diabetes mellitus (DM) were provided with a syringe specifically designed for insulin treatment in 1924, subcutaneous insulin delivery options have changed from glass to disposable plastic syringes through to insulin pens and pen needles (PNs), and insulin pumps

doi:10.3389/fcimb.2020.588517 Habtemariam S

doi: 10.1007/s10815-020-01906-3 50 ZhangTHeQXiuHZhangZLiuYChenZet al

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These may include: Lifestyle Changes: Regular exercise, avoiding caffeine and alcohol, and maintaining a consistent sleep schedule