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Indeed LC protects mitochondria from pathological events by triggering pro-survival cell signaling

The immune response in Graves disease is characterized by involvement of both Th2 and Th17 pathways, with interleukin (IL)-4, IL-6, and IL-17 contributing to B-cell activation and antibody production, while defects in immune checkpoints, such as impaired regulatory T-cell activity, promote loss of tolerance [17,18]

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doi: 10.1016/S2665-9913(20)30004-7 252 El-SayyadSMAliMAKandilLSRagabGMAbdelhamid IbrahimSS