Similarly, coronary artery disease patients with single, double, or triple-vessel stenosis and patients with acute coronary syndrome had a significant increase in malondialdehyde levels and the percentage of malondialdehyde release, associated with a marked decrease in GSH concentration, total antioxidant capacity and erythrocyte GSH peroxidase activity compared with controls (154)
Provides energy: ALC supports the transport of fatty acids to the mitochondria, where they are converted into energy especially important for tissues with high energy demand, such as the heart and muscles
With the production of adipokines and decreased activity of GPx and antioxidant capacity, the endothelium becomes deficient in nitric oxide (NO), a vasodilator, and thus promotes atherosclerotic diseases
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Ascorbate reduces it back to Fe 2+ and restores activity [134], [135]