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49 A recent systematic review and meta-analysis involving obese individuals without diabetes demonstrated that tirzepatide, semaglutide, liraglutide, and exenatide significantly increased the risk of GI adverse events compared with placebo

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Thus, an activated azygos vein shunt could reorganize blood ow and instantly attenuate the consequences of maintained occlusion-induced vascular failure, both periph- erally and centrally [ 14 20 ]