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Research on biologic stability shows that even short-term exposure to high temperatures can: Alter molecular structure Reduce binding efficiency at receptors Decrease overall drug potency This is why manufacturers provide strict storage guidelines and why proper storage directly affects treatment results

Nausea, constipation, and decreased appetite are most common, particularly during dose titration

In the Phase 2 trial, GI side effects were dose-dependent and generally mild to moderate in severity

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However, these skin reactions are considered less common than gastrointestinal side effects, and the document does not note whether these changes tend to occur on a particular part of the body, such as the face

Atypical (second-generation) antipsychotics Drug Safety Update