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Its distinctive feature is a significant stimulation of appetite via the orexigenic ghrelin pathway, increasing circulating ghrelin levels

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Excluded anyone who had previously used those drugs or had a prior diagnosis of ischemic optic neuropathy

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Questions to consider include Should my bariatric or metabolic surgery team be involved How does my surgical anatomy affect medication tolerance and dosing Are there nutritional risks that need closer monitoring How does this fit into my long term post surgical care plan Clinical guidance from the American Society for Metabolic and Bariatric Surgery emphasizes lifelong multidisciplinary follow up after bariatric surgery, particularly when additional pharmacologic therapies such as Obesity Management Medications are introduced

doi:10.1038/s41591-024-03018-2 Abdul-Rahman T, Roy P, Ahmed FK, et al