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Facial or Dental Trauma: Injury from accidents, dental procedures, or fractures can damage the trigeminal nerve or its branches, potentially triggering neuralgia

376,377,378 In a dexamethasone-induced muscle atrophy model, Ex-4 ameliorated muscle atrophy by inhibiting muscle atrophy factor and enhancing myogenic factors (MyoG and MyoD), thereby increasing muscle mass and function

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YangYWengWPengJHongLYangLToiyamaYet al Fusobacterium nucleatum increases proliferation of colorectal cancer cells and tumor development in mice by activating toll-like receptor 4 signaling to nuclear factor-B, and Up-regulating expression of MicroRNA-21

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They may recommend additional investigations to rule out other causes or suggest specific treatments if symptoms are determined to be related to hormonal changes (such as menopause) rather than the medication itself