If you used Defyne in the lips, it would probably be in the cutaneous non-red area surrounding the lip, for support (which we lose as we age)
This includes kids, older adults, pregnant and nursing moms, and those with kidney or liver problems
However, absence of extensive research on newer variants does not mean they are ineffective, just less studied
In regards to loss of weight, there is no documented outcome that supports vitamin B12 shots or injections promoting weight loss
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Injection Technique General subcutaneous guidance from clinical best-practice resources