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R.et al (1996a)

2.4 mg was the dose advanced into Phase 3 because the efficacy/tolerability ratio peaked there

These changes are especially important to note given the direct and indirect effects of alterations in claudin-1 transgenic mice of normal colonocyte differentiation program, and mucin-2 expression in a matrix metalloproteinase-9/Notch-dependent manner (Figure 2)

Cell-penetrating peptides: classes, origin, and current landscape

In both settings (with some overlapping studies), a wide range of doses have been employed, indicating at least lower bounds for efficacy (310 mol/kg)