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Choose a higher concentration from the start, or plan to reconstitute a new vial at a different concentration when you reach those dose levels

However, her lactic acid level was normal

Both compounds have a body of preclinical work in the digestive tract, so a protocol aimed at the gut lining often reaches for both

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JAMA 329, 12061216

Second, well-powered and mechanistically informed clinical trials are required to validate therapeutic efficacy, define human dosing thresholds, and ensure long-term safety