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210 , 572.e1573.e7 (2014)

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Dysbiosis of the gut microbiome observed in depressed patients can also be caused by treatment with some antidepressant drugs due to their antimicrobial activity [104]

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Significantly more women reported moderate or high sexual desire following bremelanotide vs placebo (p = 0.0114), and among women attempting intercourse within 24 hours of treatment, significantly more reported satisfaction with their level of sexual arousal following bremelanotide vs placebo (p = 0.0256) providing the foundational female sexual dysfunction dataset that directed PT-141 toward HSDD clinical development

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