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Representative images of the PVN and downstream targets of PVN GLP-1R neurons in the brain of GLP-1R-ires-Cre mice with AAV-SynaptoTag2 injected into the PVN

doi: 10.2337/dc11-1942 19 SykesAPO'Connor-SemmesRDobbinsRDoreyDJLorimerJDWalkerSet al

Efficacy and safety of an expanded dulaglutide dose range: a phase 2, placebo-controlled trial in patients with type 2 diabetes using metformin

Methods Trial design evoke (NCT04777396) and evoke+ (NCT04777409) are randomized (1:1), double-blind, placebo-controlled, parallel-group trials investigating the efficacy and safety of oral semaglutide versus placebo in participants with early-stage symptomatic AD (Fig

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