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Evidence also indicates GLP-1 therapy produces cardiovascular and metabolic improvements beyond weight loss alone, including reductions in blood pressure, inflammatory markers, and fatty liver disease risk

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In addition, semaglutide is not suitable for breastfeeding and pregnant females

Pharmacological and molecular biology studies identified GLP-1R as a high-affinity receptor expressed across diverse tissues

It is FDA-approved for chronic weight management in adults with obesity or those who are overweight with weight-related medical conditions

Clinical trials in Alzheimers patients have been largely negative