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Since the Raman spectra are dominated by the amide bands of the peptide backbone, similar to ORD and CD, it can be used for the analysis of protein secondary structure by finding correlations between the positions of the amide I and amide III vibrations and fraction of each secondary structural element present in globular proteins determined from X-ray crystal structures (Williams, 1986

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doi: 10.3389/fendo.2024.1440182 Received 29 May 2024 Accepted 26 August 2024 Published 18 September 2024 Volume 15 - 2024 Edited by Kuan-Hao Tsui, Kaohsiung Veterans General Hospital, Taiwan Reviewed by Xiuliang Dai, Changzhou Maternal and Child Health Care Hospital, China Rui Yang, Peking University Third Hospital, China Updates Copyright 2024 Zhao, Liu, Zhang, Sun, Zeringue, Meng and Ma

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