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Importantly, proteolytic cleavage of SPARC (secreted protein acidic and rich in cysteine), a matricellular protein abundantly expressed at sites of vascular injury and tissue remodeling, generates GHK-containing fragments that promote endothelial cell proliferation and neovascularization

These peptides originate from different biological contexts but share overlapping research interest in processes such as tissue repair, cellular migration, angiogenesis, and extracellular matrix remodeling

Ebrahimy F, Dolatian M, Moatar F, Majd HA

Kim M-S, et al

What concentrations are cited in the research literature for BPC-157

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